The Rabbitohs have lost Damien Cook to Covid forcing a reshuffle for their clash with the Cowboys.

The Sharks and Bulldogs have both named debutants after key players were ruled out.

Des Hasler’s injury list has grown with Morgan Harper ruled out along with Andrew Davey forcing a reshuffle to Manly’s pack.

SATURDAY

Cronulla Sharks vs Canterbury Bulldogs at PointsBet Stadium, 5.30pm AEDT

Sharks team: 1. Lachlan Miller 21. Kayal Iro 3. Jesse Ramien 4. Siosifa Talakai 5. Ronaldo Mulitalo 6. Matt Moylan 7. Nicho Hynes 8. Braden Hamlin-Uele 9. Blayke Brailey 10. Royce Hunt 11. Briton Nikora 12. Wade Graham 15. Cameron McInnes 14. Teig Wilton 16. Aiden Tolman 17. Andrew Fifita 18. Braydon Trindall. 18th man: 22. Luke Metcalf

Players cut: 2. Matt Ikuvalu 13. Dale Finucane 19. Jesse Colquhoun 20. Franklin Pele

Late Mail:Centre Siosifa Talakai returns from a shoulder injury in a timely boost with Connor Tracey out due to concussion. Andrew Fifita will come off the bench in his last home game for the club. Meanwhile, 22-year-old Kayal Iro will make his debut, replacing Matt Ikuvalu who has been withdrawn from the team due to a groin strain. Iro’s father Kevin played 34 Tests for New Zealand, and Kayal will continue the family’s strong rugby league history. Dale Finucane has also been ruled out due to a rib injury, with Cameron McInnes shifting to lock and Braydon Trindall moving onto the bench.

Bulldogs team: 1. Jake Averillo 2. Jacob Kiraz 3. Aaron Schoupp 4. Braidon Burns 5. Josh Addo-Carr 6. Matt Burton 7. Kyle Flanagan 8. Max King 9. Jeremy Marshall-King 10. Paul Vaughan 11. Josh Jackson 12. Raymond Faitala-Mariner 15. Joe Stimson 14. Zach Dockar-Clay 16. Harrison Edwards 17. Chris Patolo 25. Joshua Stuckey. 18th man: 22. Kurtis Morrin

Players cut: 13. Luke Thompson 19. Declan Casey 20. Bailey Biondi-Odo 21. Jackson Topine 23. Jeral Skelton

Late Mail:The Bulldogs will be without star enforcer Luke Thompson due to a positive Covid diagnosis. The 27-year-old missed training on Wednesday due to illness with confirmation on Thursday that Covid will rule him out of the clash with the Sharks. Joe Stimson has also revealed he was hospitalised early this week with an infected cut on his knee but will line-up on Saturday. Skipper Josh Jackson moves from lock to second row with Tevita Pangai Jr dropped to NSW Cup and Chris Patolo joining the bench. Harrison Edwards slots into lock, while Joshua Stuckey will make his NRL debut off the bench.

South Sydney Rabbitohs vs North Queensland Cowboys at Accor Stadium, 7.35pm AEDT

Rabbitohs team: 1. Latrell Mitchell 2. Alex Johnston 3. Isaiah Tass 4. Campbell Graham 19. Taane Milne 6. Cody Walker 7. Lachlan Ilias 8. Tevita Tatola 16. Siliva Havili 10. Hame Sele 11. Keaon Koloamatangi 12. Jai Arrow 13. Cameron Murray 14. Kodi Nikorima 15. Mark Nicholls 17. Thomas Burgess 22. Michael Chee Kam 18. Blake Taaffe 23. Peter Mamouzelos

Players cut: 5. Izaac Thompson 9. Damien Cook 20. Davvy Moale 21. Jed Cartwright

Late Mail: Damien Cook is out due to a positive Covid test with Siliva Havili to start and Michael Chee Kam joining the bench. Izaac Thompson is out replaced by Taane Milne on the wing. Prop Thomas Burgess is set to return from a groin injury on the bench, with Hame Sele to start and Daniel Suluka-Fifita dropping out.

Cowboys team: 1. Hamiso Tabuai-Fidow 2. Kyle Feldt 3. Valentine Holmes 4. Peta Hiku 5. Murray Taulagi 6. Scott Drinkwater 7. Chad Townsend 8. Jordan McLean 9. Reece Robson 10. Reuben Cotter 11. Luciano Leilua 12. Jeremiah Nanai 13. Jason Taumalolo 14. Tom Gilbert 15. Coen Hess 16. Jamayne Taunoa-Brown 17. Griffin Neame 18. Brendan Elliot 20. Jake Granville

Players cut: 19. Tomas Chester 21. Riley Price 22. Ben Condon

Late Mail: Scott Drinkwater switches to five-eighth for the injured Tom Dearden, with Hamiso Tabuai-Fidow to start at fullback and Tom Gilbert joining the bench.

SUNDAY

Wests Tigers vs St George Illawarra Dragons at CommBank Stadium, 2.00pm AEDT

Tigers team: 1. Daine Laurie 2. Brent Naden 3. Starford To’a 4. Asu Kepaoa 5. Junior Pauga 6. Adam Doueihi 7. Jock Madden 8. Joe Ofahengaue 9. Jake Simpkin 10. Zane Musgrove 11. Thomas Freebairn 12. Kelma Tuilagi 13. Fa’amanu Brown 14. Fonua Pole 15. Austin Dias 16. Jacob Liddle 17. Kitione Kautoga 18. Justin Matamua 19. Tyrone Peachey

Players cut: 20. James Roberts 21. Tukimihia Simpkins 22. Brandon Tumeth

Late Mail: Luke Garner (head knock), Ken Maumalo (groin), James Tamou (suspended) and Alex Seyfarth (shoulder) are all out. Junior Pauga comes onto the wing, while Tom Freebairn starts in the second row. Joe Ofahengaue moves from lock to prop, Fa’amanu Brown switches to lock and Jake Simpkin replaces him at hooker. Jacob Liddle and debutant Kitione Kautoga join the pine.

Dragons team: 1. Cody Ramsey 2. Mathew Feagai 3. Jack Bird 4. Zac Lomax 5. Tautau Moga 6. Talatau Amone 7. Ben Hunt 8. Aaron Woods 9. Jayden Sullivan 10. Blake Lawrie 11. Josh Mcguire 12. Jaydn Su’A 13. Jack de Belin 14. Tyrell Fuimaono 15. Jaiyden Hunt 16. Jackson Ford 17. Tyrell Sloan 18. Jack Gosiewski 19. Jonathon Reuben

Players cut: 20. Poasa Faamausili 21. Joshua Coric 22. Josh Kerr

Late Mail: Jack Bird switches to centre for the suspended Moses Mbye. Jack de Belin moves to lock, with Aaron Woods to start at prop.

Gold Coast Titans vs Newcastle Knights at Cbus Super Stadium, 4.05pm AEDT

Titans team: 1. Jayden Campbell 2. Sosefo Fifita 3. Brian Kelly 4. Phillip Sami 5. Greg Marzhew 6. AJ Brimson 7. Tanah Boyd 8. Jaimin Jolliffe 9. Sam McIntyre 10. Tino Fa’asuamaleaui 11. David Fifita 12. Beau Fermor 13. Isaac Liu 14. Paul Turner 15. Herman Ese’ese 16. Moeaki Fotuaika 17. Klese Haas 18. Corey Thompson 19. Jarrod Wallace

Players cut: 20. Toby Sexton 21. Esan Marsters 22. Sam Lisone

Late Mail: Centre Phillip Sami will need to pass concussion protocols to take his place. Jaimin Jolliffe starts at prop with Klese Haas to debut off the bench.

Knights team: 1. Tex Hoy 2. Edrick Lee 3. Dane Gagai 4. Krystian Mapapalangi 5. Dominic Young 6. Anthony Milford 7. Adam Clune 8. David Klemmer 9. Jayden Brailey 10. Daniel Saifiti 11. Tyson Frizell 12. Brodie Jones 13. Sauaso Sue 14. Phoenix Crossland 15. Jacob Saifiti 16. Pasami Saulo 17. Mathew Croker 18. Jack Johns 20. Enari Tuala

Players cut: 19. Chris Randall 21. Simi Sasagi 22. Jirah Momoisea

Late Mail: Tyson Frizell (ribs) and Daniel Saifiti (Covid protocols) return, with Mat Croker and Jacob Saifiti shifting to the bench.